Edited by Chance Lai
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A recent epidemiological study conducted by National Yang Ming Chiao Tung University (NYCU) has found that improved air quality is closely linked to enhanced attention and better structural integrity of brain white matter in older adults. Published in Environment International under the title “Yearly Change in Air Pollution and Brain Aging Among Older Adults: A Community-Based Study in Taiwan”, the study provides valuable insights into the potential mechanisms connecting air pollution and brain health.
Tracking Pollution’s Impact: A Decade-Long Study on Air Quality and Brain Health
The research analyzed data from 412 healthy individuals aged 60 and above residing in rural and urban communities. Using spatial models, researchers estimated the participants’ exposure to air pollutants over 10 years, including delicate particulate matter (PM2.5), nitrogen dioxide (NO2), ozone (O3), and suspended particles (PM10). Participants also underwent cognitive function tests and MRI scans to assess brain structure changes.
Bridging the Knowledge Gap: NYCU Study Unveils Air Quality’s Role in Brain Health
Although the exact mechanisms by which air pollution affects the brain remain unclear, scientists widely believe that pollutants may stimulate the immune system through olfactory pathways, triggering systemic inflammation. This process may damage the blood-brain barrier, inflame cerebral blood vessels, and ultimately impair neurological health.
Dr. Yi-Fang Chuang, Associate Professor at NYCU’s Institute of Public Health and lead author of the research, emphasized that air pollution has long been considered a significant risk factor for cognitive decline. However, research exploring the structural impact of air pollution on the brain has been limited. “Our study fills this scientific gap, demonstrating the potential benefits of improved air quality for attention and white matter integrity in older adults,” Chuang stated.
Uniting Expertise: Collaborative Efforts Unlock Key Findings
Dr. Wen-Chi Pan, Associate Professor at NYCU’s Institute of Environmental and Occupational Health Sciences, was key in interpreting the study’s data. He noted that this research is particularly significant in environmental health, as previous studies from Western countries have primarily focused on air pollution’s links to cardiovascular disease and lung cancer. Studies investigating air pollution’s impact on brain health, especially in Asian populations, have been relatively rare.
The study also benefited from the expertise of Professor Chih-Da Wu from National Cheng Kung University’s Department of Geomatics, who provided air pollution exposure estimates for participants over the past decade. His contributions were pivotal in enabling the team to identify these significant findings.
A Call for Change: Improving Air Quality for a Healthier Future
The research team stressed that improving air quality is crucial for environmental protection and a vital strategy for promoting public health, particularly in aging societies. As populations worldwide grow older, safeguarding cognitive well-being through better environmental policies becomes increasingly urgent.
By shedding light on the connection between air pollution and brain health, the NYCU study underscores the need for collective efforts — from policymakers to community members — to reduce pollutant exposure. With targeted actions to improve air quality, societies can foster healthier aging, preserve cognitive function, and enhance overall quality of life.
Source: https://www.nycu.edu.tw/
News from Research Highlights published on March 25th, 2025.
